Substitution at R3 using a halogen or alkoxy group (74f–74i) led to a slight boost in cellular potency With all the halide analogs (74g–h) displaying greatest the potency in the group. Further more optimization brought about the discovery of 74i–j, with 74k as essentially the most active compound during the https://johnnyargwj.blogginaway.com/32045498/a-review-of-indazole-carboxamide